Publication:

Regenerative touch: enhancing post-burn scar quality through autologous free fat grafting

Post-burn scars lead to functional and cosmetic deformities. Conventional treatments have limited outcomes. Autologous fat grafting has emerged as a regenerative modality. A hospital-based prospective study was conducted on 17 patients with post-burn scars (>6 months). Fat grafting was performed using a modified Coleman technique. Scar assessment was done using POSAS scale at baseline, 1 month, and 3 months. Statistical analysis was done using repeated measures ANOVA. There was a statistically significant improvement in both subjective and objective POSAS scores (p<0.001). Maximum improvement was noted in itching, thickness and pliability. Histological analysis showed collagen remodelling, increased vascularity, and reduced fibrosis. Complications were minimal, mainly transient edema. Autologous fat grafting is a safe, effective, and minimally invasive technique for improving post-burn scar quality with significant clinical and histological benefits.