Case SeriesInternational Journal of Research in Medical Sciences
Publication: Clobetasol propionate 0.025%: a topical therapeutic for skin diseases
Int J Res Med Sci. 2022;10(6):1354-1360.DOI10.18203/2320-6012.ijrms20221321
Abstract
The most widely recommended drugs for the treatment of a variety of dermatoses are topical corticosteroids (TC). These medications are approved for the treatment of inflammatory and pruritic manifestations of dermatologic disorders due to their powerful, symptom-relieving impact. Clobetasol propionate (CP) is the most popular TC used to relieve itching, redness, and edema caused by skin disorders. Topical corticosteroids exhibit anti-inflammatory, anti-pruritic, and vasoconstrictive activities. Clobetasol propionate binds to cytoplasmic glucocorticoid receptors and activates glucocorticoid receptor-mediated gene expression, resulting in the production of anti-inflammatory proteins and suppression of the production of inflammatory mediators. The effectiveness, safety, and clinical experience of utilizing CP 0.025% topical therapy for the treatment of various dermatologic disorders are discussed in this case series.
Keywords
Affiliations
- Department of Dermatology, Dr. Sadanas Skin Clinic and Laser Centre, Patiala, Punjab, India
- Department of Dermatology, Skin and Dental Care, Azamgarh, Uttar Pradesh, India
- Department of Dermatology, Skyn Stories, Gurugram, Haryana, India
- Department of Dermatology, Upasana ENT, Skin and Laser Clinic, Patparganj, Delhi, India
- Department of Dermatology, Jain Clinic, Kota, Rajasthan, India
- Department of Dermatology, Bharti Derma Care and Research Center, Amritsar, Punjab, India
- Department of Dermatology, Skin and Hair Clinic, Bandra, Mumbai, India
- Department of Dermatology, Dhamija Skin Care and Laser Clinic, Bahadurgarh, Delhi, India
- Department of Dermatology, Pooja Clinic, Alibaug, Mumbai, India
- Department of Dermatology, Skin Clinic, Sawai Madhopur, Rajasthan, India