Publication:

Fibroadenoma of the Skene’s gland: a rare paraurethral tumor in a postmenopausal female

Skene’s glands are paraurethral structures homologous to the male prostate and are an uncommon site for neoplastic lesions. Fibroadenoma, a benign biphasic tumor typically arising in the breast, is exceedingly rare in this location. A 70-year-old female presented with a 3-month history of a paraurethral swelling associated with difficulty in micturition. Local examination revealed a bright red paraurethral mass at the 11-12 O’clock position, clinically mimicking a urethral caruncle without associated discharge or bleeding. The lesion clinically mimicked a urethral caruncle and was surgically excised. Histopathological examination demonstrated a well-circumscribed biphasic lesion composed of slit-like and tubular glands within fibromyxoid stroma. The glands were lined by benign cuboidal to columnar epithelium with a preserved basal cell layer and focal apocrine change. No cytological atypia was identified. A diagnosis of fibroadenoma of the paraurethral (Skene’s) gland was made. Fibroadenoma of the Skene’s gland is an exceptionally rare entity. Histopathological evaluation is essential for diagnosis, and complete surgical excision results in excellent outcomes.