Publication:

Role of intrauterine insemination in infertile couple seeking care at Acharya Vinobha Bhave rural tertiary care hospital

Background Fibroids Infertility affects between 60 million to 68 million people worldwide; generally one in ten couples experience primary or secondary infertility. The majority of those who suffer, live in the developing world. Universally, the prevalence rises significantly with a woman’s age. The WHO estimates the overall prevalence of infertility in India to be between 3.9 and 16.8 per cent.

Objective To assess the outcome of intrauterine insemination (IUI) amongst infertile couples seeking care at AVBRH. And to correlate the outcome of IUI with various parameters associated with infertility.

Methods 50 patients undergoing 72 stimulated IUI cycles between September 2012 and august 2014. It was a prospective interventional study. Interventions: Ovarian stimulation with clomifene citrate & gonadotrophins was initiated and a single IUI was performed 36 h after triggering ovulation. Main outcome: Pregnancy rates by urine pregnancy test per couple. Pregnancy rates by urine pregnancy test per cycle. Secondary outcome: livebirth, on-going PR, abortion rate.

Results The pregnancy rate per couple and per cycle were 22% and 15.27% respectively. Live birth were 8%, on-going pregnancy was 4%, abortions were 10%.

Conclusions On the basis of analysis of successful outcome of IUI it can be said that the patients with best prognosis are the one with age <30 years, lesser duration of infertility, good motile spermatozoa, preovulatory follicle, good endometrial thickness, & semen preparation are certainly the cornerstones for successful intrauterine insemination.