Original Research ArticleInternational Journal of Otorhinolaryngology and Head and Neck Surgery
Publication: Association of hearing loss and lead exposure in a North Indian tertiary hospital: a pilot study
Int J Otorhinolaryngol Head Neck Surg. 2020;6(10):1845-1849.DOI10.18203/issn.2454-5929.ijohns20204187
Abstract
Background Lead poisoning is one of the most common metal poisonings. Lead is present in many man-made structures, work environments and various products. It has been consistently shown that low as well as high exposure levels to heavy metals have an adverse effect on human health, leading to conditions such as cardiovascular and pulmonary dysfunctions.
Methods A total of 25 patients (50 ears) presented with hearing loss were included in the study on the basis of inclusion and exclusion criterion. All the patients were subjected to pure tone audiometry and blood lead levels followed by data analysis. Statistical analysis was used and data was analysed using Statistical package for social sciences (SPSS) 21.0 software. Chi-square test and ANOVA were used to compare the data. P value less than 0.05 was considered as significant.
Results Age group of patients included in study was 5-50 years with female predominance. Blood lead levels were independent of sex and age of patient, however statistical association was noted with pure tone audiometry (hearing loss).
Conclusions As positive correlation was observed between lead levels and hearing loss, we emphasize on the fact that further studies on a larger sample size including a control arm should be planned.
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Affiliations
- Department of Personalized and Molecular Medicine, Era’s Lucknow Medical College and Hospital (Era’s University), Sarfarazgunj, Hardoi road, Lucknow, Uttar Pradesh, India
- Department of Molecular Biochemistry, Era’s Lucknow Medical College &Hospital (Era’s University), Lucknow, Uttar Pradesh, India
