Publication:

Determination of the presence of metabolic syndrome in patients of erectile dysfunction and assess correlation of its components with erectile dysfunction in a tertiary care hospital in central India

Background Erectile dysfunction (ED) is a common medical condition that affects approximately 100 million men worldwide and is currently recognized as a major public health problem. Metabolic syndrome (Met S) is a complex entity consisting of multiple interrelated factors including insulin resistance, central adiposity, dyslipidaemia, endothelial dysfunction and atherosclerotic disease, low-grade inflammation, and in males, low testosterone levels. we aimed to investigate the relationship between metabolic syndrome and ED presence and severity.

Methods Patient who came to urology OPD with c/o of ED and were evaluated for it with physical examination, questionnaire, investigations>after confirmation of ED were evaluated for presence of metabolic syndrome and its individual componentsResults: Out of these 202 patients, 98 patients were found to have metabolic syndrome. The mean age of participating patients in this study was 47.2±5.6 years. Metabolic syndrome was diagnosed in 98 (34.78%) of 202 patients. Statistically significant association was found between ED and metabolic syndrome, waist circumference and fasting blood glucose (p<0.001 with each parameter). We also found a significant correlation between hypertension and ED but no significant correlation with triglyceride levels or HDL levels.

Conclusions ED is strongly associated with metabolic syndrome and the efforts for treatment of erectile dysfunction must be made in the context of metabolic syndrome and its constituents with a low threshold to diagnose the cardiovascular disease.