Publication:

Comparative efficacy of topical hair growth serums on hair density and shedding: a double-blinded and randomized clinical trial

Background This clinical evaluation conducted with the objective of comparing the efficacy of two topical hair growth serum formulations on healthy Indian adults (men and women) suffering from hair loss, by randomized, double blinded controlled study.

Methods Two topical formulations (product A - Indulekha Bringha scalp serum and product B – 3% Redensyl in serum vehicle) were evaluated over 3 months, with a 2-week regression phase. The study included a wash out period, following which subjects were randomized in one of the treatment groups. Subjects visited the study centre once every month for their follow-up assessments during treatment period. Efficacy endpoints included anagen hair density, A:T ratio, hair pull test, hair fall assessments, scalp barrier function, and hair thickness evaluation.

Results The Indulekha Bringha scalp serum (product A) was found to be significantly efficacious in reducing hair shedding, improving hair density in all the subjects in comparison to baseline and was significantly superior to product B in the studied hair growth parameters.

Conclusions Both test products demonstrated statistically significant improvements from baseline across all evaluated hair growth parameters. However, Indulekha Bringha scalp serum (product A) showed significantly superior efficacy compared to the product B in improving Anagen density, reducing hair fall.