Publication:

Epidemiology of infective endocarditis in patients referred to Ardabil city hospital, 2010-2015

Background Infectious endocarditis is caused by bacterial or fungal infections of the endocardial surface of the heart, with high morbidity and mortality. Information on infective endocarditis is low in a developing country, and in Iran, the situation is similar, and so far no accurate research on the epidemiology of endocarditis has been carried out. The aim of study is to epidemiological evaluation of Infective endocarditis.

Methods This cross-sectional study was done on 32 patients with infectious endocarditis who referred during 2011-20166 in Ardabil city Hospital. Data from blood culture, urine test, and other diagnostic procedures were extracted from the records. Information on age, sex, the most common cause of referral, culture and positive culture, mitral valve, tricuspid and pulmonary valve involvement, underlying condition of injecting drug addiction, duration of hospitalization, clinical symptoms, type of treatment, response to Treatment, status of hospital discharge and mortality rate of patients were collected and then analyzed.

Results Of all patients, 14 (43.75%) were male and 18 (56.25%) were female. The mean age of patients was 55.6±9.4 years with a range of 21-72 years old. Patients were treated at an average of 2.2±1.4 weeks. 9 patients (28.12%) had skeletal-muscular manifestations. 26 patients (81.25%) had fever. The most prevalent microorganism was klebsiella with 71.87% that was sensitive in 13 patients (56.5%) to methicillin.

Conclusions Fever with musculoskeletal manifestations in young men with a history of injectable addiction is a common manifestation of infectious endocarditis.