Original Research ArticleInternational Journal of Basic & Clinical Pharmacology

Publication:
A prospective observational study of demographic profile in patients of amoebic and pyogenic liver abscesses in a tertiary care hospital

Int J Basic Clin Pharmacol. 2023;12(2):202-205.DOI10.18203/2319-2003.ijbcp20230387

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Abstract

Background Liver abscesses, both amoebic and pyogenic, continue to be an important cause of morbidity and mortality in tropical countries. Pyogenic liver abscess is a serious, life-threatening condition with a high mortality rate that represents a diagnostic and therapeutic challenge. In India, due to poor sanitary condition and a lower socioeconomic status, amoebiasis is endemic and amoebic liver abscess accounts for 3-9% of all cases of amoebiasis. Aim and objectives of current study was to study demographic profile in patients of amoebic and pyogenic liver abscesses.

Methods A detailed history was taken from each of these patients and all of them were subjected to a through clinical examination.

Results The highest incidence occurred in the age group 31-50 years; males were more commonly affected than females. Fever and pain abdomen were the most consistently occurring symptoms. All the patients with liver abscess had abdominal tenderness. 17 patients (74%) with liver abscess were alcoholics. 8 patients (80%) with amoebic liver abscess were alcoholic as compared to 9 patients (69%) in pyogenic liver abscess.

Conclusions Pyogenic organisms were most common cause of liver abscess.

Keywords

Affiliations

  1. Department of General Surgery, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India
  2. Department of Pharmacology, Gadag Institute of Medical Sciences, Gadag, Karnataka, India
  3. Department of Pharmacology, Kaher’s Jagadguru Gangadhar Mahaswamigalu Moorusavirmath Medical College, Hubballi, Karnataka, India

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