Publication:

A combined efficacy of cervical cerclage and vaginal progesterone use in a pregnant woman with sonographic short cervix and its outcome- an observational study in a tertiary care centre

Background Combined use of cervical cerclage procedure and vaginal progesterone administration in a women with sonographic short cervix as a treatment of cervical insufficiency is the most efficacious and safest intervention used to prevent preterm birth and neonatal morbidity/mortality.

Methods This prospective observational study was conducted in Government Villupuram Medical College and Hospital, Villupuram over a period of June, 2022- July, 2024. This study includes a observational review of 133 patients in a tertiary care centre, who undergone transvaginal cervical cerclage procedures and vaginal progesterone administration over a period of 2 years.

Results Out of 133 cases, only 100 cases were included in this study, remaining cases were dropped due to incomplete follow up and abortions. Overall efficacy of cervical cerclage and vaginal progesterone combination were expressed in terms of sensitivity as 86% which indicates the reduced incidence of preterm birth by improving latency period in terms of gestational age at the time of delivery as well as by decreasing the incidence of cervical dilatation prior to labour in our study group.

Conclusions Combination of cervical cerclage and vaginal progesterone administration in a pregnant woman with a sonographic short cervix had a beneficial impact in reducing preterm birth and significant improvement in perinatal outcomes.