Publication:

Comparative study between cyanoacrylate tissue adhesive versus skin sutures in closure of wound in 60 operated cases of open inguinal hernia

Background Today there are numerous methods available for closure of wounds like tissue adhesives, staplers, adhesive tapes and obviously the age old conventional suturing, all of which have their own pros and cons. The aim was to study the complications and results of use of 2-octyl cyanoacrylate on wound healing and compare them without those of conventional suturing.

Methods Study included 60 operated cases of open inguinal hernia. And comparison was made between cyanoacrylate tissue adhesive and conventional skin suturing in open inguinal hernia.

Results 1 out of 30 (3.3%) from tissue adhesive group and 2 out of 30(6.7%) develop fever ( P value=1.000). 4 (13.3%) of tissue adhesive and 4 (13.3%)from suturing developed redness (P value=1.000). 4 (13.3%) tissue adhesive and 5 (16.7%) from suturing had discharge (P value=0.718). 2 (6.7%) and 1 (3.3%) developed wound dehiscence from tissue adhesive and suturing respectively (P value=0.554). 1 (3.3%) from tissue adhesive developed edge eversion (P value=0.313). 24 (80%) wounds are cosmetically good in which tissue adhesive was applied and 2(6.7%) in which suturing was done (P value=0.001) which is statistically significant.

Conclusions Time required for the intraoperative application of cyanoacrylate glue is less than suturing of incision.Incidence of wound infection was found to be less when wound closure done by cyanoacrylate glue in comparison to suturing. A single linear scar was obtained using cyanoacrylate glue which is cosmetically better than suture scar.  Incidence of wound dehiscence is more in cases of application of cyanoacrylate glue than suturing.