Publication:

Non valvular atrial fibrillation stroke risk stratification by CHA2DS2-VASc score and short term outcomes

Background Atrial fibrillation confers a high risk of stroke and is associated with significant mortality and morbidity. Many scoring systems for have been proposed stroke risk stratification in atrial fibrillation. Peripheral thromboembolism, heart failure and death. The main objective of the study was to estimate CHA2DS2VASc score in cases of non valvular atrial fibrillation, to asses short term outcome in AF (stroke, thromboembolism, heart failure and death and to find out association of CHA2DS2VASc score with outcomes.

Methods 64 cases (29 M, 35 F) of non valvular AF were included in this prospective observational study.CHA2DS2VASc score was calculated and cases were categorized into low (score 0), intermediate (score 1 ) and high risk (score 2 ) for development of stroke. Cases were clinically evaluated and investigated for type, etiology, complications and comorbidities.

Results CHA2DS2VASc score was determined in 64 cases of non valvular AF. In 3 cases (4.6%) it was zero indicating low risk for stroke, 8 cases (12.5%) had CHA2DS2VASc score as 1had intermediate risk, and 53 cases (82.8%) had score 2 or more indicating high stroke risk (p 2. At the end of 3 months, total no. of cases with stroke was reported to be 5 (7.8 %). Stroke risk was significantly higher in cases of CHA2DS2VASc score>2 (p 2 demonstrated significantly high incidence for stroke as compared to those with score as zero or one (p<0.01).

Conclusions CHA2DS2VASc is a simple score to predict stroke risk in cases of non valvular atrial fibrillation and is easy to estimate. CHA2DS2VASc score ≥2; is associated with high incidence of stroke in cases of non valvular AF. CHA2DS2VASc score≥2 is associated with mortality as a short term adverse outcome in non valvular atrial fibrillation.