Publication:

Role of TSH and O-GTT screening in pregnancy induced hypertension

Background Objective of current study was to evaluate the prevalence of hypothyroidism and gestational diabetes in PIH patients and its impact on maternal and foetal outcome.

Methods A case-control study of 200 antenatal women; group A - PIH, 100 and group B normotensive - 100 women was carried out. Serum TSH and O-GTT screening was done in both groups.

Results In group A, 59% women had mild preeclampsia, 41% women had severe preeclampsia. Significantly raised TSH titre (>3 mIU/ml) was found in 36% women in group A and 9% women in group B (P value <0.0001). GDM was found in 33% women in group A and 8% women in group B (P value 0.0033).

Conclusions Incidence of both hypothyroidism (subclinical and clinical) and gestational diabetes is significantly high in women with PIH.