Publication:

Drug utilization pattern in acute coronary syndrome at tertiary care hospital: a prospective cross-sectional observational study

Background To study the pattern of utilization of drug in the patients of Acute Coronary Syndrome at tertiary care hospital.

Methods Prospective cross-sectional observational drug utilization study was conducted in patients of acute coronary syndrome admitted in ICCU, for the period of two months. Data was collected in preformed Case record form. Analysis was done by using drug use indicators, demographic pattern, morbidity pattern of disease, pattern of drug use. Data analysed using Microsoft Excel SPSS software - version 21.l. Total 71 cases were analysed.

Results In our study we analysed 71 patients out of that 50 were male and 21 were female patients. The mean age of patient was 57.61±11.09 yr; most belonging to age group of 51-60 years (36.62%). Number of patients undergoing thrombolysis were 28(39.43%) and 43(60.57%) underwent percutaneous coronary intervention (PCI). Total 44 different drugs were used and 565 drugs were prescribed in 71 patients. Most frequently prescribed drugs were Clopidogrel and aspirin in 100% encounters, followed by atorvastatin (85%).Average number of drugs per encounter was 7.96. Percentage of drugs prescribed by generic name was 16.28%.

Conclusions The present study provides valuable insight about the overall pattern of drug used in Acute Coronary syndrome. Physician should be encouraged to prescribe drugs with generic name.