Publication:

Xanthoma of the larynx: a rare mucosal presentation

Xanthoma is a reactive condition of localized collection of lipid laden histiocytes with common presentation in skin, subcutis or tendon. Musoca associated xanthomatous lesions are rare presentation. These lesions may be asymptomatic or have symptoms like throat discomfort, hoarseness. These lesions are mostly associated with dyslipidemia. Due to rarity of its presentation it can be endoscopically mistaken for polyp or malignancy. Hereby, we report a case of 42-year-old male with new onset diabetes type II. He presented to ENT OPD with change in voice for few months. He underwent nasopharyngolarngoscopy and was clinically diagnosed as vocal cord polyp. Microlaryngeal excision was done and sent for histopathology. Histopathology revealed polypoid squamous epithelium covered lesion with sheets of foamy macrophages in the stroma thus confirmed the diagnosis of xanthoma, larynx. Mucosa associated xanthoma are rare presentations and may indicate a possibility of underlying metabolic disease.