Publication:

A study of hematological profile in dengue fever at tertiary care center, Kota Rajasthan, India

Background Dengue fever continues to be one of the important public health problems in India. Dengue fever is an acute febrile disease characterized by sudden onset of fever of 3-5 days, intense headache, myalgia, retro-orbital pain, anorexia, gastrointestinal disturbances and rash. In present study we planned to study hematological profile of seropositive (Igm) dengue fever patientsMethods: A total of 100 cases were included in the study that admitted at NMCH, Kota and identified positive for IgM dengue fever.

Results Majority of case having dengue infection belong to the age group of 21-30 year (29%). Thrombocytopenia was found in 90% patients, Leucopenia in 51% patients and hematocrit value  >45%  in 13% patients. Seven patients out of 61 (11.47%) had bleeding    manifestation with platelet count between 20,000-60,000. Seven patients out of    15 (46.67%) had bleeding manifestation with platelet count <20,000.bleeding was noted in 14% of cases in which Cutaneous hemorrhagic manifestations were the most common manifestation.

Conclusions With increasing severity of thrombocytopenia there is increasing incidence of bleeding manifestation.