Publication:

Clinical correlation of ovarian mass with ultrasound findings and histopathology report

Background As the ovarian malignancy is most common among genital malignancy, the diagnosis of malignant ovarian tumour helps us to plan the treatment modality like neoadjuvant chemotherapy, chemoradiation, radiotherapy, surgery and fertility sparing surgery depending upon stage of the disease and age of the patient. This study correlates between the clinical and ultrasound findings of ovarian tumours to diagnose the nature of the tumour whether benign or malignant and offer appropriate treatment and finally correlated with histopathology report. The aim of this study was to correlate clinical, USG morphology, colour doppler indices in ovarian mass with histopathology report.

Methods This is a prospective observational study conducted at Saveetha Medical college and hospital between June 2016 to May 2017 for women who were clinically diagnosed to have ovarian mass and operated for it. These patients underwent trans vaginal (if married) or trans abdominal ultrasound and Doppler using GE S7 expert or Sonoline Acuson x300 (siemens) or Philips HD 11xE. Based on clinical findings and on the characterization of the image in USG and colour doppler findings it will be concluded whether the mass is benign or malignant. This is correlated with HPE report.

Results Out of 113 women studied ovarian mass diagnosed clinically as benign in 78%and malignant in 21%. USG prediction of ovarian cancer was 88.00% sensitivity, 80.68% specificity. When Doppler findings were included sensitivity was 91.43% and specificity was 91.03%. The combined use of clinical and USG with Doppler for diagnosis of ovarian malignancy was 92.31% sensitive and 95.95% specific. The positive predictive value of combined use of clinical and USG with Doppler for diagnosis of ovarian malignancy was 92.31%.

Conclusions From this study clinical, USG and Doppler are important modalities in diagnosing benign or malignant ovarian tumour. When both are combined the diagnostic value is extremely high. This aids in planning the management.