Publication:

Trends of lipid abnormalities among newly detected type-2 diabetes mellitus in a tertiary care hospital in Karnataka, India

Background Diabetes mellitus is a common and a chronic disease with chronic complications and constitutes a substantial burden for both patient and health care system. Insulin resistance and type 2 diabetes are associated with a clustering of interrelated plasma lipid and lipoprotein abnormalities, which include reduced HDL cholesterol, a predominance of small dense LDL particles, and elevated triglyceride levels. Aims and objectives were to study the pattern of lipid abnormalities in newly detected type-2 diabetic patients.

Methods A cross sectional study was conducted at Vijayanagara Institute of Medical Sciences Hospital and College, Bellary from May 2014 to November 2014. A total of 300 newly detected diabetic patients were included in the study. Blood Examination was done to estimate low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides (TG).

Results Out of 300 patients, lipid abnormality was seen in 200/300 (66.67%) of the patients. Increased LDL noted in 152 (50.67%), triglycerides in 112 (40.67%), decreased HDL in 130 (43.34%) of patients.

Conclusions It is clearly evident that dyslipidaemia is very common association of type 2 diabetes mellitus, and culprit of majority diabetic related cardiovascular mortality.