Original Research ArticleInternational Journal of Basic & Clinical Pharmacology
Publication: Wound healing and anti-inflammatory activity of extract of Ficus racemosa linn. bark in albino rats
Int J Basic Clin Pharmacol. 2012;1(2):111-115.DOI10.5455/2319-2003.ijbcp001212
Abstract
Background F. racemosa is an indigenous plant having anti-secretory, anti-diabetic, anti-ulcer etc. properties. It is used widely in the ayurvedic medicines.
Methods The experimental models of wound and inflammation were used to assess the wound healing and anti-inflammatory properties of F. racemosa. The significance of differences was analyzed using students’ ‘t’ test.
Results In the strength of 10% local application it could apparently enhanced the process of healing. At the dose of 20 mg/100 gm intraperitoneally it could show inhibition of carageenan induced acute inflammation at 3rd, 5th and 7th hour and at the dose of 30 mg/100 gm intraperitoneally, formalin induced subacute inflammation was inhibited till 4th day. The results were found statistically significant.
Conclusions Aqueous extract of F. racemosa has got wound healing and anti-inflammatory activity. It is likely that the duration of action may be shorter.
Keywords
Affiliations
- Department of Pharmacology, C.U. Shah Medical College, Surendranagar 363001, India
- Department of Pharmacology, GCS Medical College, Hospital and Research Centre, Ahmedabad 380025, India
