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Original Research ArticleInternational Journal of Basic & Clinical Pharmacology

Publication:
Wound healing and anti-inflammatory activity of extract of Ficus racemosa linn. bark in albino rats

Int J Basic Clin Pharmacol. 2012;1(2):111-115.DOI10.5455/2319-2003.ijbcp001212

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Abstract

Background F. racemosa is an indigenous plant having anti-secretory, anti-diabetic, anti-ulcer etc. properties. It is used widely in the ayurvedic medicines.

Methods The experimental models of wound and inflammation were used to assess the wound healing and anti-inflammatory properties of F. racemosa. The significance of differences was analyzed using students’ ‘t’ test.

Results In the strength of 10% local application it could apparently enhanced the process of healing. At the dose of 20 mg/100 gm intraperitoneally it could show inhibition of carageenan induced acute inflammation at 3rd, 5th and 7th hour and at the dose of 30 mg/100 gm intraperitoneally, formalin induced subacute inflammation was inhibited till 4th day. The results were found statistically significant.

Conclusions Aqueous extract of F. racemosa has got wound healing and anti-inflammatory activity. It is likely that the duration of action may be shorter.

Keywords

Affiliations

  1. Department of Pharmacology, C.U. Shah Medical College, Surendranagar 363001, India
  2. Department of Pharmacology, GCS Medical College, Hospital and Research Centre, Ahmedabad 380025, India

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