Publication:

Contribution of various factors to male infertility: a prospective review

Infertility is becoming a serious problem among present generation. It causes emotional instability and mental stress in affected couples. In half of the analysed cases, male factor infertility is the major contributor. Despite numerous efforts by researchers to identify various causes of male infertility, about 70 % causes remain unknown. This is due to lack of understanding of mechanisms involved in male infertility. The present review focuses on the abnormalities in male reproductive structures and contribution of endocrinological, immunological and developmental factors to male factor infertility.