Case ReportInternational Journal of Basic & Clinical Pharmacology
Publication: Fatal Stevens-Johnson syndrome induced by phenytoin: a case report
Int J Basic Clin Pharmacol. 2013;2(6):843-845.DOI10.5455/2319-2003.ijbcp20131237
Abstract
Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare (one to two per 10,00,00 population per year) but life threatening adverse drug reactions. Drugs commonly implicated are anti-epileptics, anti-microbials and non-steroidal anti-inflammatory drugs (NSAIDS). Amongst anti-epileptics, carbamazepine and phenytoin are the major culprits. We report here a fatal case of SJS due to phenytoin.
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Affiliations
- Department of Pharmacology, Govt. Medical College, Nagpur-440003, Maharashtra, India
- Department of Neurosurgery, Superspeciality Hospital, Govt. Medical College, Nagpur-440003, Maharashtra, India