Publication:

Diagnostic dilemma in a case of jaundice complicating pregnancy with successful maternal outcome in a tertiary care centre

Approximately 3% of all pregnancies are complicated by liver biochemical test abnormalities, the most life-threatening of which is acute fatty liver of pregnancy (AFLP). We report a case of 32 years G2A1 patient, with IVF conceived DCDA twin pregnancy at 30+3 weeks gestation with intra-uterine death of one fetus with preterm prelabour rupture of membrane with meconium-stained liquor along with a history of jaundice from her 5th month of gestation. Her biochemical parameters were suggestive of early signs of disseminated intravascular coagulation. Acute fatty liver of pregnancy was suspected while keeping in mind other differentials and the patient was managed by prompt delivery and a multi-disciplinary team approach. High index of suspicion of the condition in women presenting with jaundice in pregnancy, can prevent maternal mortality and morbidity.