Publication:

Efficacy and safety of Y-spur in the treatment of male infertility disorders: an open-label clinical endpoint study

Background Idiopathic male infertility has a complex etiology that includes oxidative stress, hormonal dysregulation, genetics, lifestyle choices, and environmental pollutants that can affect spermatogenesis and lower the quality of sperm. A polyherbal formulation, Y-Spur Capsule contains various herbs that support reproductive health through different methods, improve semen quality, lowers oxidative stress, and increase sperm count, motility, morphology, and testosterone levels.

Methods 30 males aged 18-45 years, diagnosed with idiopathic male infertility were enrolled in the study and followed for 9 months.

Results Statistically significant and sustained improvements were observed over a period of 9 months compared to their baseline values in a.  semen volume (1.85±0.48 to 2.11±0.51), b. sperm concentration (11.6±1.96 to 17.7±2.37), c. total sperm count (14.4±3.06 to 22.93±2.32), d.  total motile sperm (14.1±2.92 to 50.13±6.27), e. normal sperm morphology (2.67±0.48 to 11.47±1.87) (p=0.0001).

Conclusions The progressive improvement in sperm morphology and motility further supported the overall enhancement of sperm quality and reproductive potential and the safety evaluations confirmed that Y-Spur was well tolerated. In addition, Y-spur was well tolerated among the subjects and was considered safe when consumed over a period of 9 months.