Publication:

A prospective observational study on clinical profile and maternal outcome of pregnant women with PROM greater than 28 weeks to onset of labour

Background Prelabour rupture of membranes (PROM) is a common obstetric condition associated with significant maternal morbidity. This study aimed to study clinical profile, associated etiological factors and maternal outcome in pregnancy with PROM.

Methods This prospective observational study was done at a tertiary health care centre in south Gujarat. All consenting women with PROM (28 weeks to onset of labour) admitted in labour room of a tertiary health care centre in south Gujarat were enrolled in this study.

Results Majority of patients belonged to age group of 18-25 years (53.3%). Majority of the patients were from normal BMI (76.3%), literate (62.7%), primigravida (54.7%). The majority of women 66.7% presented with leaking per vaginum, while 33.3% presented with abdominal pain without cervical dilatation with incidental detection of PROM. With respect to gestational age, 58% of pregnancies resulted in term delivery, while 42% resulted in preterm delivery. In our study 69.33% had moderate anemia, 25% had positive high vaginal swab for bacterial vaginosis. 70.3% had poor bishop’s score, 61.3% of our subjects requires induction of labour, 79.7% subjects had leaking to delivery interval was >12 hours. In this study, 54.6 cases underwent LSCS. Most common indication of LSCS was fetal distress (48.8%). Puerperal pyrexia was the most common maternal complication (14.3%), 30.7% of our subjects had lactational failure.

Conclusions PROM is a significant obstetric condition associated with increased maternal morbidity. Infection-related complications are the major contributors. Early diagnosis, timely antibiotic therapy, and appropriate obstetric management can significantly improve maternal outcomes.