Publication:

Mycophenolic acid: a drug with a potential beyond renal transplantation

Mycophenolic acid is an anti-metabolite immunosuppressant. It inhibits the enzyme inosine monophosphate dehydrogenase, which is essential for purine synthesis. It is indicated in prevention of rejection after renal transplantation. It is one of the few drugs, which were discovered more than a century ago and still in active use. This review discusses the other current and potential uses of the drug.