Publication:

A study of Helicobacter pylori infection in patients of ischemic cerebro vascular stroke

Background The objective of the study was to study the prevalence and association of Helicobacter Pylori infection in patients of ischemic cerebrovascular stroke. Observational analytic cross sectional study.

Methods Seroprevalence of infection by H. pylori was assessed by History, examination, CT scan Brain, Rapid Urease Test and Elisa in 39 patients with acute cerebral ischemia and 30 age and sex matched control subjects selected randomly from general population with similar socio economic status. The presence of carotid plaques instability was evaluated by color doppler ultrasound.

Results Hypertension (61.54%) and previous history of cerebral ischemia are clinically significant leading cause of cerebral ischemia among the patients (p 0.05).

Conclusions Our results support the hypothesis of an association between infection with H. pylori and acute cerebral ischemia and there is no significant association found between H. pylori seropositivity and carotid plaque instability.