Publication:

Manifestation of pernicious anaemia as hyperpigmentation of palms and soles

Vitamin B12 deficiency produces various manifestations involving CNS, heart, skin, blood and female reproductive systems. It is seen most commonly in the older individuals, malabsorptive states (>60% of all cases) and vegetarians. Pernicious anaemia may be confused to Addison’s disease as both may present with similar clinical features. Hereby we report a case of pernicious anaemia presenting with dermatological manifestation in the form of deep pigmentation of both palms of and both soles respectively, cortisol levels normal so Addition’s disease ruled out.