Publication:

Correlation between associating factors of obstructive airway disease with obstructive sleep apnoea

Background Several researchers reported that OSA may contribute to asthma symptoms and severity. But, the relation between associating factors of obstructive airway disease with obstructive sleep apnoea was not well documented. Therefore, the present study has been undertaken to investigate the relation between associating factors of OAD with obstructive sleep apnoea.

Methods Pulmonary Function Test was done for assessing air flows and measuring absolute and predicted values of FEV1, FVC, FEV1/FVC and MMEF. PFT was interpreted as normal if FEV1/FVC >70 as per GOLD and >75 as per GINA, with normal FEV1 and normal FVC. Decreased FEV1, Decreased FVC, Decreased FEV1/ FVC, predicted ( 0.05). The Sleep Stages in the study group (OAD and No OAD group) was also statistically insignificant except for Stage III. The PFT-FEV1was found to be statistically significant (p=0.043) when compared between OAD group and in the No OAD group.

Conclusions Due to the consequences of the overlap syndrome, it is recommended to actively search for existence of OSA, and to treat it with continuous positive airway pressure (CPAP) concurrently with oxygen and optimal pharmacological treatment.