Publication:

Retrospective analysis of biochemical profile of dengue infection in a tertiary care hospital

Background Dengue is an exceedingly common infection of the tropics. The aim of the research to study the biochemical parameters of serologically proven dengue cases.

Methods The study included Dengue patients admitted in PSG Hospital between January 2011and December 2012.

Results Analysis of aspartate aminotransferase results showed that 19.1% had two-fold rise, 13.3% had three-fold rise and 19.6% had more than threefold rise. Analysis of alanine aminotransferase showed that 35.7% had normal values, 14.95% had two-fold rise, 11.1% had three-fold rise and 11.5% had more than threefold rise. Serum proteins were normal in 35.7% and low in 19.6%. Analysis of serum albumin showed low values in 10.6% Serum sodium levels were low in 11.1% of patients. Albuminuria was positive in 53% of patients. Serum ionised calcium levels were low in 26.8% of patients.

Conclusions The biochemical abnormalities noted in our study included include elevated liver enzymes, low sodium and ionised calcium levels, hypoalbuminemia and increased urine albumin excretion.