Publication:

Comparison of lipid profile in diabetic patients presenting with cardiac diseases

Background Diabetes mellitus (T2DM) is the most common metabolic disorder in human beings. It is a group of metabolic disorders which causes a decrease in the insulin secretion and /or resistance in its functions and/ or actions. It is the commonest prevalent metabolic disorder which is rapidly increasing all over the world. The purpose of this study was to evaluate the serum lipid levels in diabetic patients who presented to the OPD or the IPD with cardiac diseases.

Methods It was a cross sectional observational study conducted for period of 18 months (June 2018-December 2019). Study was done in 111 patients diagnosed with T2 DM (diagnosed according to ADA criteria) attending OPD and in admitted in the Rohilkhand Medical College and Hospital (RMCH), Bareilly, Uttar Pradesh.

Results A total of 111 patients were taken for this study and in the present study we found that 47.7% patients had Coronary artery disease (CAD), 21.6% had myocardial ischemia (SMI), 36% diastolic dysfunction (DF) and 28,8% had systolic dysfunction (SDF). About half of the patients were above 50 years (50.5%) followed by 40-50 (47.7%) and <40 years were in a small number (1.8%). More than half of the males (56.6%) and 28.6% of females were in 40-50 years of age.

Conclusions We found in our study a significant association of high triglyceride levels with the silent myocardial ischemia (SMI) in diabetic patients but no significant relation with the high levels of cholesterol.