Publication:

Study of salivary α-amylase immunoglobulin, a and flow rate in diabetic subjects: a cross sectional study

Background Diabetes is possibly the mainly common metabolic syndrome with salivary inference. However, lack of literature on the possible relationship between diabetes and salivary α-amylase, Immunoglobulin-A (IgA) and flow rate. Therefore, present study aims to estimate of salivary α-amylase, immunoglobulin-A and flow rate in diabetic subjects of Indian population.

Methods The present cross sectional study was done on 60 subjects of diabetes mellitus (T2DM) and 60 subjects’ non-diabetic healthy controls at Banas medical college and our hospital. The subject’s demographic and anthropometric parameters were recorded; detailed history and clinical examination were performed in the entire cases. The un-stimulated saliva was collected in the fasting state. Salivary flow rate, biochemical variables and IgA were analyzed. Data which was collected was statistically analyzed.

Results The results showed that salivary glucose (p 0.05) between diabetic and non-diabetic subjects.

Conclusions In our study, we conclude that significant differences were reported in salivary flow rate, α-amylase and IgA between diabetics and non diabetics. Therefore, we suggested that estimation of salivary parameters might be a cost effective and a non invasive choice for screening, diagnosis and monitoring of diabetes instead of blood.