Publication:

Histopathological evaluation of small biopsy of bone: a retrospective study in tertiary care hospital of north east India

Background Bone tumors are infrequently encountered disease constituting only 0.5% of the total world cancer incidence. There are worldwide variations in different bone lesion and patterns of bone cancer. Histologic evaluation is one of the first prerequisites in evaluating any primary bone tumor.

Methods The present study was carried out at the Gauhati Medical College and hospital (GMCH), Guwahati, Assam for a period of 2 years. Cases of bone biopsy from the histopathology section of GMCH were reviewed and analyzed.

Results We found that bone lesions were common in <20 years of age, having a male predilection. Osteomyelitis was the most common non-neoplastic lesion; among neoplastic most common benign tumor was osteoclastoma and metastatic adenocarcinoma was the most common malignant bony lesion.

Conclusions Preoperative histopathological analysis of bone biopsy is very valuable in diagnosis as well as planning of surgical procedure specifically in case of neoplastic bone lesion and proper management of non-neoplastic lesion. Therefore, biopsy and radiology together aid in correct diagnosis of bony lesions.