Publication:

Platelet/albumin ratio and plateletcrit levels are potential new biomarkers for assessing acute myocardial infarction: hospital based cross sectional study

Background Platelet activation plays a key role in acute myocardial infarction (AMI). Plateletcrit and platelet/albumin ratio are potential new biomarkers, but their diagnostic accuracy for AMI is unclear.

Methods This was a hospital-based cross-sectional study on 90 patients- 45 with AMI, 45 with unstable angina (UA). Plateletcrit and platelet/albumin ratio were compared between groups and ROC analysis was done to determine predictive accuracy for AMI.

Results Plateletcrit (0.49±0.04 versus 0.35±0.03, p 0.72 differentiated AMI from UA with 82% sensitivity and 84% specificity.

Conclusions Plateletcrit and platelet/albumin ratio were significantly elevated in AMI compared to UA patients. These biomarkers demonstrated good diagnostic accuracy for detecting AMI at admission. Further large-scale studies are warranted to validate these findings before incorporating into clinical practice.