Publication:

Aerobic capacity in adults with mild hemophilia compared to healthy adults: a cross-sectional study

Background Hemophilia is an X-linked inherited bleeding disorder that not only affects the joints, and muscle but can also affects other organs. It has been determined that aerobic capacity protects individuals with hemophilia (PWH) from joint impairment. The impact of aerobic capacity on PWH, however, is little understood. Evaluation of aerobic capacity in individuals with hemophilia is a critical aspect of comprehensive care. The integration of these assessments helps tailor the management strategies accordingly.

Methods 30 participants (males) with the age group of 18-30 years were selected via a convenient sampling method. 30 participants were divided into 2 groups, the hemophilic group (15) and the control group (15). The aerobic capacity was measured with a 6-minute walk test and Queen College step test.

Results Results from the study showed a mean value of 6-minute walk test and Queen College step test in the control group was 450.8 m 42.5 ml/kg/minute and in the hemophilic group was 324 m 25.7 ml/kg/minute respectively. The data also revealed that the aerobic capacity of the control group and hemophilic groups differed statistically significantly.

Conclusions Hemophilia affects aerobic capacity in a significant way. These findings highlight the need for attention in physical activity prescription and promotion for patients with hemophilia and need to engage in aerobic or resistive exercise for their health benefits.