Case ReportInternational Journal of Research in Medical Sciences

Publication:
PLA2-R positive primary membranous nephropathy: a case report

Int J Res Med Sci. 2025;13(2):853-856.DOI10.18203/2320-6012.ijrms20250267

Thumbnail Image
View on the journal's website(opens in a new tab)

Abstract

Membranous nephropathy (MN) is a significant cause of nephrotic syndrome in adults, often linked to the presence of circulating antibodies against phospholipase A2 receptor (PLA2R). This case report details the clinical presentation, diagnostic process, treatment, and outcomes of a patient diagnosed with PLA2R-positive membranous nephropathy. The report highlights the importance of early diagnosis and personalized treatment strategies, demonstrating the evolving landscape of MN management. A brief review of the literature related to the topic is also presented. For this purpose, a search was made in freely accessible sources, selecting those with the most relevant and up-to-date information.

Keywords

Affiliations

  1. Department of Internal Medicine, Clinica Hospital Mérida, ISSSTE. Facultad de Medicina, Universidad Autonoma de Yucatán (UADY), Merida, Yucatán, México
  2. Department of Nephrology, Hospital Regional "Dr. Valentín Gómez Farías", ISSSTE. Guadalajara, Jalisco, México

Full item record