Original Research ArticleInternational Journal of Clinical Trials

Publication:
Perioperative management of hyperglycemic patients undergoing surgery: an observational cross sectional study in a tertiary care hospital

Int J Clin Trials. 2024;11(3):182-187.DOI10.18203/2349-3259.ijct20242000

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Abstract

Background Diabetes poses an additional risk during anesthesia, yet there is a lack of sufficient Indian data on perioperative antidiabetic drug use and its implications. This droves us to conduct the study.

Methods Cross-sectional, observational study, conducted in a tertiary care hospital's general surgery and orthopaedics wards. Data collected from the first anaesthetist visit to 24 hours postoperative period included antidiabetic medications, anesthesia drugs, blood sugar levels, co-morbidities, concomitant medications, and intravenous (IV) fluids. Descriptive statistics and parametric tests were used for analysis.

Results The study comprised 180 patients (62.8% males, median age 56 years), with diabetes duration predominantly between 1-5 years (28.3%). Preoperatively, metformin was the most prescribed oral hypoglycemic agent (72.2%), decreasing to 56.67% postoperatively. Intraoperatively, only 1.6% received insulin, while 98.4% received no drugs. Common postoperative antidiabetic agents included insulin BD (n=48). General surgery (73.3%) and orthopedics (26.7%) contributed 132 and 48 patients, respectively, with spinal anesthesia (68.3%) and bupivacaine (75.4%) being most prevalent. Blood glucose during surgery was effectively monitored. Hypertension (52.8%) was the most common co-morbidity, and Ringer lactate (60.8%) was the predominant IV fluid.

Conclusions Adequate perioperative antidiabetic management was observed in hyperglycemic patients.

Keywords

Affiliations

  1. Department of Pharmacology, Seth G. S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
  2. Department of Anaesthesiology, Seth G. S. Medical College and KEM Hospital, Mumbai, Maharashtra, India

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