Publication:

Dynamics of degradation of new samples of membrane coating based on cellulose polymers

Background The use of polymeric coating implants is a promising way of preventing adhesion disease and its related complications in the peritoneum. In this paper, the dynamics of degradation of new samples were studied in an in vitro experiment. A sample was then chosen which is potentially suitable for further research in an in vivo experiment.

Methods In the research, 7 different samples of polymeric coating were studied viz. No. 81 MN, No 82. MN, No. 83 MN, No. 84 MN, No. 85 MN, No. 86 MN and No. 87 MN - developed by Lintex, LCC (St. Petersburg) together with the department of Operative Surgery and Topographical Anatomy named after A.D. Myasnеkov of Kursk State Medical University. The samples were differentiated by subjecting them to different technological processing of temperature, and chemical agents etc.

Results In the course of the experiment, it was discovered that the rate of degradation of the polymeric coating implants depended on their processing methods.

Conclusions Membranes that quickly undergo degradation cannot be used for prophylaxis of complications caused by surgical interventions.