Publication:

Invasive micropapillary carcinoma breast: a rare entity

Invasive Papillary Carcinoma(IPC) is an uncommon breast disease, constituting 0.5% to 1% of all breast carcinomas. It is distinguished by the papillary structural design: proliferation characterized by finger-like projections or fronds composed of central fibrovascular cores covered by epithelium, without myoepithelial cell layer. The combination of a residual palpable mass and a frankly bloody aspirate at the fine needle aspiration is a strongest indicator of carcinoma. Clinical and Radiological manifestations of IPC are not specific. Papillary carcinomas may present as bloody nipple discharge, an abnormal mass, or radiographic abnormalities. Therapeutic management of IPC is still controversial. Treatment-related information for patients with papillary carcinoma is limited, and patterns noted in available series suggest a variable approach to this disease.