Publication:

Prevalence of subclinical hypothyroidism in cases of cholelithiasis

Background This prospective study was carried out to analyse the prevalence of subclinical hypothyroidism in patients of gall stones.

Methods A prospective study was carried out in the Gandhi Medical College and associated Hamidia Hospital Bhopal from 2015 to 2016. Data was collected from patients who were admitted in surgical wards, with a provisional diagnosis of cholelithiasis. Patient was diagnosed cholelithiasis on abdominal ultrasonography and was tested for having subclinical hypothyroidism by testing fasting blood samples for serum TSH.

Results A total of 50 patients of cholelithiasis were included in present study. Females were 42 out of 50 (84%) and males were 8 out of 50 (16%). Most common age group was 41-50 (36%) correct (insignificant at p 1cm and overall 58% stones were >1cm (statically significant P<0.05). 03 out of 12 hypothyroidisms (25%) patient had single stones while 9 (75%) patient have multiple stone (statically significant P value <0.05). In hypothyroid cases most stones were of cholesterol type (58%) (Statically significant at P value≤0.05).

Conclusions Early diagnosis of hypothyroid state at subclinical level by monitoring TSH level so that they can be treated at early stages and burden of Cholelithiasis thus can be prevented.