Publication:

Solitary plasmacytoma: a rare entity

Plasmacytoma is a plasma cell disorder characterized by localized accumulation of neoplastic monoclonal plasma cells in bone, or in soft tissues with no skeletal component, without any evidence of systemic involvement as demonstrated by the lack of clonal plasma cells in the bone marrow and absence of features of end organ damage. Spine plasmacytoma is a rather common entity, but solitary occurrence is not. It is usually described as a single lytic lesion without signs of myeloma cells, which is later diagnosed on radiological investigations and confirmed on bone marrow examination and histopathology examination. Imaging diagnosis is extremely helpful in early diagnosis and planning appropriate treatment. We present a case of a 55 year old female with pain bilaterally in lower limbs. A routine MRI shows focal lesion in the right pedicle of L4 vertebrae with bulging discs.