Publication:

Abdominal wall metastasis and hyponatremia in metastatic renal cell carcinoma

Renal cell carcinoma (RCC) is a frequently encountered urological malignancy. It accounts for 2% to 3% of all adult malignant neoplasms, and usually carries a poor prognosis. About one third of patients with RCCs have distant metastases at the time of diagnosis and in one fourth, metastasis occurs despite radical nephrectomy. The most frequent sites of metastasis include lung (50-75%), bone (30-40%), liver (30-40%), brain and thyroid (25%). Subcutaneous metastases are uncommon, with very few reported cases and typically imply a poor prognosis (3.4% incidence). Hyponatremia is a poor prognostic marker in malignancy and is rarely associated with RCC. We report a case of metastatic anterior abdominal wall nodules and hyponatremia in a 65 years old gentleman diagnosed with left renal cell carcinoma.