Publication:

The relationship between colorectal polyps and colon cancer with Helicobacter pylori infection

Background Our aim in this study is to determine the relationship among Helicobacter pylori (HP) with colon cancer and colorectal polyps. Thus, colorectal cancers (CRC) can be diagnosed at an early stage, the progression of the disease can be prevented and a contribution can be made to prolonging the life span of the patients.

Methods The 75 patients as the case group and 150 patients as the control group were included in the study. Patients with family history of CRC and clinical symptoms  who had total colonoscopy in a tertiary hospital between 31/09/2021 and 31/03/2022 and underwent gastroscopic gastric biopsy and evaluated for HP were included. The patients were divided into three groups as patients with colorectal polyps, CRC and normal patients.

Results HP positivity was more common in patients with cancer history than those without cancer history (p<0.001). In the analyzes performed, HP positivity was more common in patients with cancer than in patients without cancer (p<0.001). Concordantly, more polyps were detected in HP positive patients than in non-HP patients (p=0.001). In the analyzes performed, HP infection was significantly higher in patients with CRC and colorectal polyps compared to normal controls.

Conclusions HP positive patients can be evaluated in terms of CRC and colorectal polyp.