Publication:

A study on thyroid function test in children with nephrotic syndrome

Background This is a comparative study which was conducted to find out any impact of nephrotic syndrome on status of thyroid hormone level in children with nephrotic syndrome.

Methods Study was done from December 2014 to December 2015 at a tertiary care hospital in BBSR, Odisha. The study was carried out in total of  60 children of age between 1-8 years out of which 30 children(N group) were admitted for reason other than nephrotic syndrome(excluding known cases of thyroid disorder) and 30 children were  suffering from nephrotic syndrome (NS group). Thyroid hormone level (T3, T4 and TSH) was tested in all children.

Results The T4 and T3 levels in nephrotic syndrome (NS group) patients were low. TSH level were high in NS group. T4 level was low in NS group in comparison to N group which was statistically significant. Hypothyroidism was found more in younger children 6 years which was statistically significant.

Conclusions This study concluded that incidence of hypothyroidism was more in children with nephrotic syndrome.