Publication:

Response to 13 cis retinoic acid in metatstatic neuroblastoma

Neuroblastoma is the most common extra cranial solid tumour of childhood, with 5 year survival rate of 40%-50% in high risk group. Surgery, chemotherapy, radiotherapy, high dose chemotherapy with stem cell transplant and retinoid therapy are treatment options for neuroblastoma. Here we present a 5 year female child presenting with abdominal pain for 1 month and abdominal distension for 3 weeks, and underwent biopsy after necessary investigations, and diagnosed to have high risk neuroblastoma and treated with multiple lines of chemotherapy and attained complete response after retinoid therapy. The case is presented because of complete response achieved with retinoid therapy with tolerable side effects.