Publication:

Role of clinical laboratory parameters in management of dengue infection, beyond infancy: a tertiary care experience

Background Dengue infection is the most rapidly spreading mosquito-borne viral disease in the world affecting millions of children all over the world with varied clinical features. This study was done to study the clinical profile of children in a tertiary teaching hospitalMethods: This is a prospective observational study, all children with features suggestive of dengue infection as per WHO 2012 guidelines were enrolled in the study. Their demographic data was collected and after through clinical examination and initial stabilization they we categorized and treated accordingly.

Results A total of 92 children were enrolled, males were 56.5% and females 45.6%, and most of the children were from Bangalore and neighbouring state Andhra Pradesh. Fever constituted the major compliant while pain abdomen with vomiting was the major warning sign. Thrombocytopenia was seen in 95.6%. Majority required IV fluids (69.5%) whole ventilation was required in 8.6%.the overall mortality was 8.6%.

Conclusions Dengue fever is a dynamic disease with heterogeneous manifestation. The treatment many range from simple IV fluids to Ventilator support. Good clinical monitoring will identify those children developing shock and institute early treatment.