Review ArticleInternational Journal of Basic & Clinical Pharmacology

Publication:
A review on: nutraceutical and neuropotective approaches of Momordica charantia L. fruits against neurodegenerative disease

Int J Basic Clin Pharmacol. 2024;13(5):739-745.DOI10.18203/2319-2003.ijbcp20242440

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Abstract

The Momordica charantia is a tropical plant, also known as bitter gourd or bitter melon, is a crucial herbal remedy with a wide range of medicinal properties. People in Indian subcontinent and China consider, M.charantia as key components to treats variety of elements such as cancer, diabetes and neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, multiple sclerosis etc. These diseases are described by degeneration or loss of selective neuron populations in a progressive manner. The two main characteristic of neurodegenerative illness are oxidative stress and inflammation, which have been studying using the variety of medicinal herbs and their derivatives.  However, very few authors have reported the protective effects of M. charantia against neurodegenerative diseases.  This short review focus on the neuroprotective effects of M. charantia. Based on their anti-oxidant and anti-inflammatory properties, the present study emphasizes to further explore the protective effects of M. charantia against neurodegenerative and neuroinflammatory diseases.

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Affiliations

  1. Department of Zoology, Centurion University of Technology and Mangement, Bhubaneswar, Jatani, Khordha, Odisha, India

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