Publication:

Psychiatric crisis to abdominal tuberculosis

We report a case of a 15-year-old female presenting with alprazolam overdose, psychiatric symptoms, and subsequent diagnosis of ileocecal tuberculosis (TB). Initial management addressed acute overdose and psychiatric illness, followed by identification of TB through imaging, colonoscopy, and histopathological confirmation. Drug-induced liver injury (DILI) complicated first-line anti-TB therapy, necessitating a modified regimen.  This case highlights the diagnostic challenges in patients with overlapping psychiatric and systemic presentations, underscoring the critical role of thorough clinical and diagnostic evaluation in adolescents presenting with psychiatric symptoms and gastrointestinal complaints and the importance of monitoring for hepatotoxicity during ATT.