Publication:

Study the components of metabolic syndrome in preeclampsia

Background Long term health implications in women who develop hypertensive disorders of pregnancy (HDP) include an increased risk of developing cardiovascular diseases (CVD) later in life. So based on this the present study was undertaken to investigate parameters of metabolic syndrome in normal pregnant and preeclamptic women.

Methods Serum HDL cholesterol, serum triglycerides, fasting blood sugar levels and blood pressure (systolic and diastolic) were estimated in 100 normal pregnant women (controls) and 100 pregnant women with preeclampsia (cases) and comparison between cases and age matched controls of age group 18-35 years done using ‘z’ test. Study was carried out between 2011 to 2015. All statistical analyses were performed using GRAPH PAD PRISM version 5.00 software and Microsoft Office Excel 2007 software.

Results Serum triglyceride (TG), fasting blood sugar levels and blood pressure (systolic and diastolic) were significantly elevated (p < 0.0001) while high density lipoprotein (HDL) was significantly decreased (p < 0.0001) in preeclamptic group than in control group.

Conclusions Serum triglyceride (TG), fasting blood sugar levels and blood pressure (systolic and diastolic) were significantly elevated (p < 0.0001) while high density lipoprotein (HDL) was significantly decreased (p < 0.0001) in preeclamptic group than in control group.