Publication:

Change of LDL and HDL levels in patients with acute coronary syndrome on admission and 3 months after treatment

Background The heart ischemic disease has become considerably prevalent worldwide and causes about one-fifth of deaths. Hyperlipidemia is a risk factor for atherosclerosis that includes hypercholesterolemia and hyperlipidemia.  The aim of this study was to study the change in the level of LDL and HDL on admission and 3months after treatment in patients with acute coronary syndrome (ACS).

Methods This is a case-series study that has been done on 180 patients with acute coronary syndrome. 24 hours after admission, the lipid profile was checked for patients and the amounts of LDL and HDL were registered. After drug prescription and three mounts later the levels of LDL and HDL were rechecked and compared.

Results 64.4% were men and the average age was 54.46 years. 34.44% were with diabetes, 32.7% were with high blood pressure, 46.6% with hyperlipidemia background, and 56.7% with smoking background. Compare the amounts of LDL, cholesterol and triglyceride after three months showed that the levels of them were decreased significantly.

Conclusions The results of this study showed that after 3 months of treatment, the mean of LDL level was more than the target range (70 mg/dl) that this may be due to inadequate dose of drug, irregular use, improper education to patient and irregular follow-up.